Prenatal screening for Down's syndrome.
نویسندگان
چکیده
Balanced and accurate information about Down's syndrome. The fact that screening does not give a definite diagnosis. An explanation of the risk score obtained following screening. The screening pathway and next steps for screen-positive and screen-negative results, including information about the decisions that need to be made at each step and their consequences. Information about amniocentesis and chorionic villus sampling.
منابع مشابه
Survey of prenatal screening policies in Europe for structural malformations and chromosome anomalies, and their impact on detection and termination rates for neural tube defects and Down's syndrome
OBJECTIVE To 'map' the current (2004) state of prenatal screening in Europe. DESIGN (i) Survey of country policies and (ii) analysis of data from EUROCAT (European Surveillance of Congenital Anomalies) population-based congenital anomaly registers. SETTING Europe. POPULATION Survey of prenatal screening policies in 18 countries and 1.13 million births in 12 countries in 2002-04. METHODS...
متن کاملThe Prevention of Down's Syndrome in the South Western Region of England 1975–1985
Cytogenetic prenatal screening for Down's syndrome in the South West Region of England from 1975 to 1985 was reviewed. The use of amniocentesis increased, and for the years 1981 to 1985 averaged 29.4% of women 35 years or over at their estimated date of delivery. 58 pregnancies were terminated after karyotyping of amniotic fluid cells confirmed trisomy 21. 385,440 live births were born in the r...
متن کاملChronic constipation in long stay
syndrome. In: Grudzinskas JG, Chard T, Chapman M, Cuckle HS, eds. Cambridge: Cambridge University Press, 1993 (in press). 25 Laundon C, Spencer K, Macri JN, Buchanan P. Tumer syndrome detection by MSAFP/Free Beta (hCG) screening. J Med Genet 1993;30:340-1. 26 Spencer K, Mallard AS, Coombes EJ, Macri JN. Prenatal screening for trisomy 18 with free f3 human chorionic gonadotrophin. BMJ 1993 (in p...
متن کاملExplaining variation in Down’s syndrome screening uptake: comparing the Netherlands with England and Denmark using documentary analysis and expert stakeholder interviews
BACKGROUND The offer of prenatal Down's syndrome screening is part of routine antenatal care in most of Europe; however screening uptake varies significantly across countries. Although a decision to accept or reject screening is a personal choice, it is unlikely that the widely differing uptake rates across countries can be explained by variation in individual values alone.The aim of this study...
متن کاملUptake, outcomes, and costs of implementing non-invasive prenatal testing for Down’s syndrome into NHS maternity care: prospective cohort study in eight diverse maternity units
OBJECTIVE To investigate the benefits and costs of implementing non-invasive prenatal testing (NIPT) for Down's syndrome into the NHS maternity care pathway. DESIGN Prospective cohort study. SETTING Eight maternity units across the United Kingdom between 1 November 2013 and 28 February 2015. PARTICIPANTS All pregnant women with a current Down's syndrome risk on screening of at least 1...
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ورودعنوان ژورنال:
- The New England journal of medicine
دوره 314 23 شماره
صفحات -
تاریخ انتشار 1986